Since the 1970s a series of high exposure events, such as the use of Agent Orange in Vietnam and the contamination of Love Canal in New York State, has led to significant public attention concerning the health and environmental effects of chlorinated dioxins and furans. The 17 “most toxic” of these compounds have been targeted for virtual elimination by many governments worldwide and have resulted in pollution controls, international agreements, definition of regulatory limits, and recommendations around consumption of certain foods. AXYS has conducted dioxin analysis since 1988 and continues to lead in their analysis. In 1996, AXYS was one of a small handful of laboratories to meet the criteria of a World Health Organization study of human plasma and milk analysis for chlorinated dioxins/furans and dioxin-like PCBs.
AXYS has qualified as an EPA Dioxin Contract Laboratory and is accredited by CALA and NELAC (New York, Florida, California, New Jersey, and Washington) for analysis of chlorinated dioxins and furans in multiple matrices. Required measurements are usually in the pg/L range for water and in the pg/g range for soils, sediments, biosolids, tissue, and serum. The selectivity and sensitivity of high resolution mass spectrometry (HRMS) is usually a requirement for measurement of these compounds. AXYS provides regulatory compliant analyses (MLA-017) with accompanying documented QA/QC and has extensive experience in the analysis of a variety of industrial, environmental and biomonitoring matrices including blood serum and other human tissues. Our specialized sampling and analytical procedures may allow for much lower detection limits and reduced sample sizes in human and sediment matrices.
Polychlorinated Dioxins and Furans are a group of chemically-related compounds that are extremely toxic, persistent, and bioaccumulative environmental contaminants that result predominantly from human activity such as waste incineration, forest fires and certain industrial activities. Analysis of chlorinated dioxins and furans is required to ensure industrial emissions meet regulatory standards, to track sources of on-going emissions, to monitor the food supply, to identify contaminated sites, to provide input into risk assessments and to contribute to human health assessment by measuring body burdens. AXYS uses accredited high-resolution mass spectrometric (HRMS)-based methods to measure dioxins and furans to industry leading low detection limits. AXYS specializes in measurement of chlorinated dioxins and furans to picogram or lower concentrations from standard sample sizes.
Dioxin precursors Dibenzo-1,4-dioxin and dibenzofuran are non-chlorinated aromatic compounds with a dioxin and furan backbone. They are regulated in pulp and paper mill defoamers and some other paper/pulp industry materials by Environment Canada due to the formation of chlorinated dioxins and furans including 2,3,7,8-TCDD and 2,3,7,8-TCDF from the chlorine-bleaching process. AXYS provides services for the measurement of dibenzodioxin (DBD) and dibenzofuran (DBF) concentrations in defoamers, pulp, oils, waxes, anthraquinone, and oil-based and water-based formulations using a method based on Environment Canada Reference Method EPS 1/RM/20. Samples are analyzed by GC-MS, and can also be analyzed by GC-HRMS, if required.
Baseline PBDE Levels Established in Lake Ontario
In collaboration with the New York State Department of Environmental Conservation, analysis of high volume Lake Ontario surface water samples collected on XAD-2 resin and filters for PBDEs, PCBs, dioxins and furans, and OC pesticides in 1999 resulted in a joint publication “Establishing Baseline Levels on PBDEs in Lake Ontario Surface Water”.
Metro Vancouver Multi-Year Project to Study POPS and CECs loading in WWTP and diffusion in the Receiving Environment
AXYS has provided Alkylphenol, Sterols and Hormones, Dioxins, PCB congeners, PAHs, Alkylated PAHs, Pyrethroids, and Organochlorine Pesticides analysis for the characterization of WWTP effluent, storm water/ CSO effluent, and its subsequent diffusion to receiving waters and receiving water sediments. Resident fish are also measured on a scheduled basis.
Supporting Great Lakes AOC Investigations
AXYS provided analysis for the Great Lakes Area of Concern Investigation, including ambient water, high-volume sampling, precipitation, fish and sediment samples. Axys tested for PAHs, Dioxins, PCBs, OC pesticides including chlorobenzenes, current use pesticides (OC, ON, OP, triazine, pyrethroids), perfluorinated compounds, PBDPE, and PPCPs.